A matchup with the banged-up, struggling New England Patriots was just what the San Francisco 49ers needed following back-to-back losses on the road.

The New England Patriots came out on the losing end decisively in Sunday’s Week 4 loss to the San Francisco 49ers. It didn’t take the 49ers long to blow the game wide open, and once they did, they never looked back.

Want to watch the Patriots play the 49ers? Here's everything you need to stream Sunday's 4:05 p.m. ET game on Fox.

That day-to-day designation was given to the other five players hurt as well. Wide receiver Jacob Cowing has a shoulder issue, defensive tackle Jordan Elliott is working through a knee injury, tight end George Kittle is dealing with a rib injury, WR Chris Conley has an oblique injury, and fullback Kyle Juszczyk has a shoulder injury.

San Francisco 49ers coach Kyle Shanahan said on Monday that star linebacker Fred Warner is day to day this week after missing the second half of Sunday's victory over the New England Patriots, adding that the week will give him "a chance to heal up.

A great day for 49ers star linebacker Fred Warner turned sour quickly just before halftime, as the leader of the San Francisco defense left the game with an ankle injury and did not return. Warner’s absence wasn’t enough to allow the Patriots to get back into the game,