Christina Applegate has shared the grueling effects of her battle with Multiple Sclerosis. The “Dead To Me” actress, who was diagnosed with MS in early 2021, has been open

Christina Applegate has shared the horrific experiences she goes through living with multiple sclerosis (MS). The star was diagnosed with the condition following advice from fellow actor Selma Blair, who she confided in about strange symptoms she was experiencing.

In the three years since Christina Applegate was diagnosed with multiple sclerosis, the actress' medical condition has steadily progressed. During a recent episode of her podcast MeSsy - co-hosted with Jamie-Lynn Sigler,

"Everybody has different ways of it showing up,” Applegate said in the November 5 episode of her MeSsy podcast, which she co-hosts by with The Sopranos actress Jamie-Lynn Sigler, who also struggled MS and talks about her experiences on the program. “I lay in bed screaming. Like, the sharp pains, the ache, the squeezing.”

In a candid discussion on her MeSsy podcast, Christina Applegate shares the painful realities of living with Multiple Sclerosis, including sharp pains and debilitating symptoms that impact her daily life.

"I can't even pick up my phone sometimes because now it's travelled into my hands, so I'll, like, try to go get my phone or get my remote to turn on the TV or sometimes, I can't even hold them. I can't open bottles now.

The "Married... with Children" alum also revealed that the disease has "traveled into my hands" and makes it difficult to pick up objects.